BDBM10887 Sulfamate 7::Topiramate (TPM)::US11535599, Example topiramate::[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl sulfamate
SMILES CC1(C)O[C@@H]2CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1
InChI Key InChIKey=KJADKKWYZYXHBB-XBWDGYHZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 10887
Affinity DataKi: 3.5nMAssay Description:Ki value against human carbonic anhydrase XII (hCA XII)More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of human membrane bound carbonic anhydrase 12 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO...More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of human recombinant transmembrane carbonic anhydrase 12-mediated CO2 hydration activity after 15 minsMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of human carbonic anhydrase 12 catalytic domain by CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of human carbonic anhydrase 12 catalytic domain preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of human cloned CA12 catalytic domain by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of human recombinant CA12 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of human recombinant CA12 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of human carbonic anhydrase 12More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of human transmembrane carbonic anhydrase 12 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.80E+3nMAssay Description:Inhibitory constant against catalytic domain of human carbonic anhydrase XIIMore data for this Ligand-Target Pair
Affinity DataKi: 3.80E+3nMAssay Description:Inhibition of human carbonic anhydrase 12 by CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+4nMAssay Description:Inhibition of recombinant human CA12 pre-incubated for 15 mins measured by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair